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ALine provides Microfluidic Solutions to Pharmaceutical, Biotech, and Medical Device Companies

Our vision is a world where microfluidic-based diagnostics and research tools are widely available to promote better stewardship of our lives and our planet.  We think rigorously and focus on the “why”; enabling product engineering to move with urgency and clarity. Optimism and enthusiasm inform our day to day work, while we strategize to minimize the impact of potential roadblocks. Our core values: make a difference, continuously improve.

We provide expert engineered solutions for commercial-ready microfluidic products to realize your dreams.

ISO 13485:2016 Certified

Experts

Over 50 years of industry experience; track record of commercial success

Certified

Program Management Professionals retire technical risk, and ensure DFM

Integrated

Design, engineer, and manufacture under one roof.

Microfluidic Cartridges

ALine designs, troubleshoots, and engineers commercial-ready, single-use Diagnostic Cartridges for Point of Care and Rapid Testing. Expert problem solvers with experience spanning all sample types and a wide range of assays.

Microfluidic Manifolds

Multiplexed fluid handling manifolds for Life Science Instrumentation. These advanced microfluidic manifolds reduce dead volume and enable gradient generation. Our expertise in on-board valves is unmatched.

Microfluidics for Cell Culture

ALine has pioneered the implementation of microfluidics for cell culture and organ-on-a-chip applications. Whether it’s in Space or in the Pharma discovery lab,  Our state-of-the-art solutions facilitate groundbreaking research.

Microfluidic Wearables

We offer commercial solutions for microfluidic wearables, designed for pharmaceutical and consumer applications. These wearable devices support athletes, and IoT applications.

Internet of Things

ALine’s expertise was foundational in the development of a family of high performance gas sensors for remote and distributed sensing.  The Interlink gas sensing technology facilitates the IoT for industrial and consumer applications.

Cell Culture In Space

ALine pioneered a cell culture card for NASA Ames’ GENESAT mission to explore the affects of weightlessness and radiation on living systems.  ALine works with many companies to explore commercial applications of space on biology.

ALine’s Cell Culture Card Flies On NASA’s First GENESAT Space Mission

Our Leadership Team

Dr. Leanna Levine, President and CEO ALIine

Leanna M. Levine, PhD

CEO and Founder

Stefano Begolo

Stefano Begolo, PhD, PMP, MBA

Director of Engineering

Dr. Travis Holloway

Travis Holloway, PhD

Sr. Lead Engineer

Mr. Antonio Pineda, ME, Technical Sales Engineer

Antonio Pineda, BSME

Technical Sales Engineer

Our microfluidic device engineering processes are supported with a range of tools including: modeling software, breadboard instruments, CNC machining, injection molding, laminate fluid circuit technology and die-cutting, and quality assurance tools and processes for both prototyping and pilot production and assembly under an ISO 13485 certified quality system. 

ALine's Phased Microfluidic Engineering Process

Design – Engineer – Manufacture —> ALined

ALine implements a phased engineering development process for microfluidic design that provides transparency and clarity, ensuring key milestones are met, while providing clients easy access to all program documentation.

Learn More
ALine Phased Development Phase 0
ALine Phased Development Phase 1
ALine Phased Development Phase 2
ALine Phased Development Phase 3

Our facility supports all aspects of the microfluidic device engineering effort: modeling software, engineering maker space, breadboard instrumentation, wet lab testing, dedicated production equipment, quality assurance tools, and cleanroom assembly.

Recognized Microfluidic Industry Pioneers

ALine is a highly regarded industry leader in microfluidics. We are a founding member and active participant in prestigious organizations such as the Microfluidics Association, CADMIM, and NextFlex. ALine has been honored with the Medical Design Excellence Award, Supplier to a Winner for our exceptional contributions to the field. We continue to pioneer applications and publish with our clients as we advance the field.  

What They’re Saying

“

Our work with ALine allowed us to rapidly prototype multiple generations/versions of microfluidic chips with good quality to validate our biology. The cost of the chips came down rapidly with scale.

Duleek RanatungaCEO Pear-Bio
“

We have enjoyed working with the team at ALine. Their professionalism and expertise have helped us meet and exceed our development timelines. We look forward to continuing to work with them in the future.

Alex RussomanoFounder, CEO New Haptics
“

The team at InSilixa enjoys working with the professional and knowledgeable partners we found with ALine Inc. The expertise and vision at ALine supported us more than once successfully. It is pleasure doing business with ALine inc.

Piyush SavaliaSr. Manager, Manufacturing Engineering, Insilixa
“

We have been working with ALine on a few projects, across two different companies in the last several years, and find the quality, responsiveness, and knowledge of the ALine team accelerates and adds value to our development.

Wendell SuCEO, Mobiosense
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The hands-on, collaborative approach has been the best and most surprising part of our experience with ALine. Our technology includes components outside of what ALine produces, such as pumps and hydrogels. We sent these components to the ALine facility so the microfluidic chip designs could be built and tested for compatibility with everything else in the system, which saved us a lot of future headaches trying to fit everything together.

Duleek RanatungaCEO, Pear Bio
“

ALine's commitment to speed and quality has been extremely valuable to Epicore's product development efforts across multiple programs. ALine has continued to meet our manufacturing needs in support of beta testing and new product launches.

Roozbeh GhaffariCEO, Co-founder, Epicore

ALine Microfludics Case Studies

See Case Studies

ALine Microfluidics Videos

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ALine - The Microfluidic Experts

Unlock the Power of Microfluidic Devices for Your Scientific Innovations to Create Life-Changing Products

1

Precision and Accuracy

Microfluidic devices provide unparalleled precision and accuracy in fluid manipulation, enabling you to achieve reliable and reproducible results. With intricate microchannels and controlled flow rates, you can trust in the precise handling of even the smallest volumes of liquids.
2

Speed and Efficiency

Say goodbye to time-consuming and labor-intensive processes. Microfluidic devices streamline workflows by automating fluid handling, reducing manual errors, and accelerating experimentation and analysis. Experience faster results without compromising quality.
3

Miniaturization and Cost Savings

The power of miniaturization with microfluidic devices. These compact systems enable you to perform complex assays and experiments in a smaller footprint, requiring fewer reagents and samples. This not only saves costs but also conserves valuable resources.
4

Versatility and Flexibility

Microfluidic devices offer a wide range of applications across various industries, from biomedical research and pharmaceutical development to environmental monitoring and diagnostics. With their modular designs, these devices can be customized and tailored to suit specific experimental requirements, ensuring flexibility and versatility.
5

Integration and Compatibility

Integrate microfluidic devices into existing workflows. Incorporate microfluidics into your research effortlessly.
6

Advancements in Life Sciences

In the field of life sciences, microfluidic devices have revolutionized areas such as cell culture, organ-on-a-chip models, and high-throughput screening. Experience enhanced control over cellular microenvironments and explore complex physiological processes reproducibly.

Unlock the full potential of your research and take advantage of the numerous benefits that microfluidic devices offer. ALine, a leading microfluidics company, combines expertise, innovation, and a proven track record of success to the  development of state-of-the-art microfluidic products. Contact us today to embark on your journey towards groundbreaking discoveries and transformative solutions.

Contact ALine

Awards


ALine Awarded Patent for Sequencing Manifold

Certifications

ISO 13485:2016 certification
FDA 21 CFR Part 820 compliant

Resources

Technical Articles
Academic Papers
Application Notes
Case Studies
Materials, Design Rules, Guides & Manuals
Videos
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Signal Hill, CA 90755
Ph: +1-877-707-8575
Email: info@alineinc.com

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